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Topic Overview: Tuberculosis (TB) transmission can and does occur in hospitals and other healthcare settings. TB investigations in these settings pose unique challenges and opportunities to detect and prevent TB. This presentation will review a large TB outbreak that was identified in a small community in California. Many healthcare workers were exposed and became infected with TB; four healthcare workers developed active TB disease linked to this outbreak. Working together with public health and infection control practitioners, occupational health providers are playing a key role in investigating TB transmission, identifying infected healthcare workers, developing appropriate ongoing plans for TB evaluation, and offering preventive treatment. The outbreak investigation methods, including the role of TB genotyping and whole genome sequencing, will be reviewed. The issue of visitors to healthcare facilities being potential sources of TB will also be discussed.
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